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Comprises a β-catenin-targeted stapled peptide
CAS Number: 4079-26-9
GJ103 sodium salt is water soluble
Blocking CRM1-mediated nuclear export can result in the suppression of tumors
CEP-32496 Hydrochloride - CAS# 1227678-26-3 entin enacarbil Comprises a β-catenin-targeted stapled peptideAgerafenib, also known as RXDX 105, CEP 32496 and AC013773, is an orally available v raf murine sarcoma viral oncogene homolog B1 (B raf) serine threonine protein kinase inhibitor with potential antineoplastic activity. CEP 32496 specifically and selectively inhibits the activity of the mutated form (V600E) of B raf kinase. This inhibits the activation of the RAF mitogen activated protein kinase kinase (MEK) extracellular signal related kinase (ERK)