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In an IL-8-dependent air pouch model
The first class (DuP-753 sensitive) represents approximately 85% of the total binding sites for AII and possesses a high affinity (IC50 of 92
PF 4995274
J Med Chem
Febuxostat 5132 In an IL-8-dependent air pouchFebuxostat, also known as Uloric and TMX 67, is a xanthine oxidase inhibitor used to treathyperuricemia and chronic gout. Product information CAS Number: 144060 53 7 Molecular Weight: 316. 37 Formula: C16H16N2O3S Synonym: TEI 6720 TMX 67 Uloric FBX Chemical Name: 2 [3 cyano 4 (2 methylpropoxy)phenyl] 4 methyl 1,3 thiazole 5 carboxylic acid Smiles: CC1N=C(SC=1C(O)=O)C1=CC(C#N)=C(C=C1)OCC(C)C InChiKey: BQSJTQLCZDPROO UHFFFAOYSA N InChi: InChI=1S
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