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PubMed PMID: 17085670
Molecular Pathways: Endothelial Cell FAK-A Target for Cancer Treatment
including the BETs
BRD-7552 increases PDX1 expression in mouse αTC cells but not βTC cells
GSK-923295 - CAS# 1088965-37-0 size:2mg solid PubMed PMID: 17085670GSK 923295, CAS No. 1088965 37 0, also known as GSK 923295A, is a novel antimitotic inhibitor of centromere associated protein E (CENP E) with potential anticancer activity. GSK 923295A demonstrated significant antitumor activity against solid tumor models, inducing CRs in Ewing sarcoma, rhabdoid, and rhabdomyosarcoma xenografts. Clinical study showed that GSK 923295 had dose proportional pharmacokinetics and a low number of grade 3 or 4 adverse
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