CGH 2466 dihydrochloride 485luxametamide Chemical Name: N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3

Chemical Name: N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3

Solubility: DMSO: 36 mg/mL(199

in spontaneously hypertensive rats

CAS Number: 2158266-58-9

CGH 2466 dihydrochloride 485luxametamide Chemical Name: N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3CGH 2466 dihydrochloride is a combined adenosine receptor antagonist. It is an inhibitor of phosphodiesterase type 4 and p38 mitogen activated protein kinase. It inhibited the phosphodiesterase 4D (PDE4D) isoenzyme with an IC50 value of 225 nM. It inhibited the p38 mitogen activated protein (MAP) kinases and with IC50 values of 18718, 40038 nM, respectively . There are four adenosine receptor subtypes of the G protein coupled receptor family,