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regulating deubiquitination activity of USP10 and USP13 by Beclin1 provides a mechanism for Beclin1 to control the levels of p53
8-Dimethyl-5-phenethyl-2
is an inhibitors of ERK protein kinase
cleaved-caspase3
Vemurafenib - CAS# 918504-65-1 0069 regulating deubiquitination activity of USP10Vemurafenib, CAS No. 918504 65 1, also known as PLX4032, RG7204 or RO5185426, is an orally bioavailable, ATP competitive, small molecule inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. Vemurafenib received FDA approval for the treatment of late stage melanoma on August 17, 2011. Vemurafenib selectively binds to the ATP binding site of BRAF(V600E) kinase and inhibits its activity, which may result in an inhibition of an over
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