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Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats
InChi: InChI=1S/C21H22ClN3O2/c1-4-18-19(22)20(25(3)24-18)21(26)23-13-15-7-11-17(12-8-15)27-16-9-5-14(2)6-10-16/h5-12H
respectively) or in human hepatocytes (AC50 for cell loss at 48 hours was >125 μM based on results in three assessments in two different human hepatocyte lots (LBN and HU4165)
InChiKey: IIDJRNMFWXDHID-UHFFFAOYSA-N
Spermidine 7786 Positive allosteric modulation of GABA-ASpermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2. contents. Product information CAS Number: 124 20 9 Molecular Weight: 145. 25 Formula: C7H19N3 Chemical Name: (4 aminobutyl)(3 aminopropyl)amine Smiles: NCCCCNCCCN InChiKey: ATHGHQPFGPMSJY UHFFFAOYSA N InChi: InChI=1S C7H19N3 c8 4 1 2 6 10 7 3 5 9
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