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InChi: InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H
Smiles: CC1=CC=C(C=C1NC1=CC2NC(=O)/C(=C\C3=CC=CN3)/C=2C=C1)NC(=O)NC1=CC(=CC=C1F)C(F)(F)F
57(10):4213-38
Favipiravir-RTP does not inhibit the human DNA polymerase α
NV-5138 C AR Degrader-4 TFA InChi: InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13HNV 5138 is an orally and centrally active small molecule drug for the treatment of major depressive disorder (MDD). It directly and selectively activates the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway by binding to and modulating sestrin2, a leucine amino acid sensor and upstream regulatory pathway. The mTORC1 pathway is the same signaling pathway that the NMDA receptor antagonist ketamine activates in the medial prefrontal