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At the transfected human α4β2 neuronal nAChR in K177 cells
the half-life of OR-1896 is about 75 to 80 h allowing cardiovascular effects to persist up to 7 to 9 days after discontinuation of a 24-hour infusion of levosimendan
03 mg/kg/day
66(1):404-11
PIM-447 dihydrochloride - CAS# 1820565-69-2 Catalog No.:M16461-C At the transfected human α4β2PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone protective effects. PIM447 dihydrochloride induces apoptosis. Product information CAS Number: 1820565 69 2 Molecular Weight: 513. 38 Formula: C24H25Cl2F3N4O Chemical Name: N {4 [(1R,3S,5S) 3 amino 5
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