ZJ 43 60075 Smiles: CC1C[C@@]2(C)OC=1[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@H]2O[C@@H]1O[C@H](C)C[C@@H]([C@H]1O)N(C)C

Smiles: CC1C[C@@]2(C)OC=1[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@H]2O[C@@H]1O[C@H](C)C[C@@H]([C@H]1O)N(C)C

Chemical Name: {2-[(3-aminopropyl)amino]-1-sulfanylethoxy}phosphonic acid trihydrate

APC 366 (TFA) (5 mg/kg/0

Amlexanox increases phosphorylation of TBK1 on Ser172 in 3T3-L1 adipocytes

ZJ 43 60075 Smiles: CC1C[C@@]2(C)OC=1[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@H]2O[C@@H]1O[C@H](C)C[C@@H]([C@H]1O)N(C)CIC50: 2. 4 nM ZJ 43 is a N acetylaspartylglutamate (NAAG) peptidase inhibitor. The peptide neurotransmitter N acetylaspartylglutamate (NAAG) is reported to act as an agonist at group II metabotropic glutamate receptors. NAAG is inactivated by extracellular peptidase activity leading to yielding glutamate and N acetylaspartate. In vitro: As a potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III) with Kivalues of 0. 8 and 23 nM