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Thiamine diphosphate analog 1 2894 E3 Ligase Ligand-Linker Conjugates 54

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Description

E3 Ligase Ligand-Linker Conjugates 54

that rats treated with suprapharmacologic doses of Ertiprotafib show signs of PPAR family activation

dosing in multiple established human tumor significantly inhibits tumor activity(P R547 inhibits tumor growth up to 95% in the HCT116 human colorectal tumor xenograft model in nude mice

as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s=31

Thiamine diphosphate analog 1 2894 E3 Ligase Ligand-Linker Conjugates 54Thiamine diphosphate analog 1 is an analog of Thiamine diphosphate. Thiamine diphosphate is the active form of vitamin B1. Thiamine diphosphate a universal cofactor involved in pivotal cellular pathways. Product information CAS Number: 2606 90 8 Molecular Weight: 303. 17 Formula: C6H11NO7P2S Chemical Name: ({hydroxy[2 (4 methyl 1,3 thiazol 5 yl)ethoxy]phosphoryl}oxy)phosphonic acid Smiles: CC1N=CSC=1CCOP(O)(=O)OP(O)(O)=O InChiKey: UFUUMZHATZTWCW

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