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LY-411575 (isomer 3) nserin 2008 Mar 27

SKU: 44683259699

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Description

2008 Mar 27

doses of MK-8776 S-isomer associate with robust biomarker activation and improved tumor response are not associated with enhanced toxicity of gemcitabine on hematological parameters in BALB/c mice

IC50 value:Target: opioid antagonistWhen responding over the entire 30 min operant session was examined

increase the percentage of polarized cells in an aged HSC population

LY-411575 (isomer 3) nserin 2008 Mar 27LY 411575 isomer 3, is an isomer of LY411575, which is a potent, cell permeable secretase inhibitor (IC50= 0. 078 nM 0. 082 nM (in membrane assay in cell based secretase assays)) and also inhibits Notch clevage (IC50= 0. 41 nM). Product information CAS Number: 2070009 28 6 Molecular Weight: 479. 48 Formula: C26H23F2N3O4 Synonym: LY411575 isomer 3 LY 411575 isomer 3 Chemical Name: (2R) 2 [(2R) 2 (3, 5 difluorophenyl) 2 hydroxyacetamido] N [(10S) 8

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