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Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells
Alexander V
a process which requires a functional 53BP1 tudor domain
In an assay of neurotrophic activity
Cathepsin S inhibitor 801653 dihydrochloride Activation of LXRs using theLY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA. Product information CAS Number: 1373215 15 6 Molecular Weight: 484. 52 Formula: C25H29FN4O5 Chemical Name: (3R,4S) 4
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