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2016 Apr 6
Emixustat potently inhibits isomerase activity in vitro (IC50=4
Formula: C10H6O2
Necrotic cell death is determined by measuring lactate dehydrogenase (LDH) release from cells
ML786 dihydrochloride Catalog No.:M19993-C 2016 Apr 6ML786 dihydrochloride is a potent and orally bioavailable Raf inhibitor, with IC50s of 2. 1, 4. 2, and 2. 5 nM for V600EB Raf, wt B Raf, and C Raf, respectively. ML786 dihydrochloride also inhibits Abl 1, DDR2, EPHA2, KDR, and RET (IC50=<0. 5, 7. 0, 11, 6. 2, 0. 8 nM). ML786 dihydrochloride can be used for the research of cancers. Product information CAS Number: 1237536 18 3 Molecular Weight: 611. 48 Formula: C29H31Cl2F3N4O3 Chemical Name: (Z) 3 (2
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