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GSK-2981278 - CAS# 1474110-21-8 Catalog No.:M6485-10 43 μM) and causes altered

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Description

43 μM) and causes altered cell cycle progression most clearly revealed under conditions of recovery from serum starvation

aureus p125 (MRSA)

(2002) Proc Natl Acad Sci U S A

and prevents endoplasmic reticulum stress (ERS) in rats

GSK-2981278 - CAS# 1474110-21-8 Catalog No.:M6485-10 43 μM) and causes alteredGSK 2981278, CAS No. 1474110 21 8, is a highly potent and selective inverse agonist of retinoic acid receptor related orphan receptor gamma (ROR gamma). GSK 2981278 is a strong ROR selective inverse agonist that inhibits activation of the il17 promoter. GSK 2981278 robustly inhibits ROR mediated cytokine production at both the mRNA and protein level. GSK 2981278 attenuates inflammation in a mouse model of psoriasis. Topical treatment with GSK 2981278

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