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selective and CNS penetrating blocker of Kir7
Malantide TFA is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts
22)28-31(23
In nude mice bearing human tumor xenografts of GL07
Annonacin 0860 selective and CNS penetrating blockerAnnonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex. Annonacin is the active agent found in Graviola leaf extract to act as an inhibitor of sodium potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps. Product information CAS Number: 111035 65 5 Molecular Weight: 596. 88 Formula: C35H64O7 Chemical Name: (5S) 5 methyl 3 [(2R,8R,13R) 2,8,13 trihydroxy 13 [(2R,5R) 5 [(1R) 1