3-Isomangostin phenylpyruvic acid InChi: InChI=1S/C31H44N4O11/c36-25-11-10-24(29(40)34-25)35-30(41)22-8-7-9-23(28(22)31(35)42)32-12-13-33-26(37)20-45-16-5-1-3-14-43-18-19-44-15-4-2-6-17-46-21-27(38)39/h7-9

Name: 3-Isomangostin phenylpyruvic acid InChi: InChI=1S/C31H44N4O11/c36-25-11-10-24(29(40)34-25)35-30(41)22-8-7-9-23(28(22)31(35)42)32-12-13-33-26(37)20-45-16-5-1-3-14-43-18-19-44-15-4-2-6-17-46-21-27(38)39/h7-9
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InChi: InChI=1S/C31H44N4O11/c36-25-11-10-24(29(40)34-25)35-30(41)22-8-7-9-23(28(22)31(35)42)32-12-13-33-26(37)20-45-16-5-1-3-14-43-18-19-44-15-4-2-6-17-46-21-27(38)39/h7-9

Carbachol (500 ng) does not affect REM sleep but enhances wakefulness in the rat

VU0467485 (AZ13713945) shows selectivity for M4 over human and rat M1/2/3/5

3)>kidney (24

3-Isomangostin phenylpyruvic acid InChi: InChI=1S/C31H44N4O11/c36-25-11-10-24(29(40)34-25)35-30(41)22-8-7-9-23(28(22)31(35)42)32-12-13-33-26(37)20-45-16-5-1-3-14-43-18-19-44-15-4-2-6-17-46-21-27(38)39/h7-93 Isomangostin, extracted from Garciniamangostana. L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3 Isomangostin would be an attractive chemical tool for the development of anticancer agents. Product information CAS Number: 19275 46 8 Molecular Weight: 410. 46 Formula: C24H26O6 Chemical Name: 5,9 dihydroxy 8 methoxy 2,2 dimethyl 7 (3 methylbut 2 en 1 yl) 2,3,4,6 tetrahydro 1,11 dioxatetracen 6 one Smiles:

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