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JAK1-IN-4 uinol A InChiKey: HGWLTZOMQZIUBW-UHFFFAOYSA-N

SKU: 6772289975

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Description

InChiKey: HGWLTZOMQZIUBW-UHFFFAOYSA-N

Bacteriochlorophylls c

1-6H3/t16-

Discovery of a Novel Dual Histone Deacetylases (HDACs) and Mammalian Target of Rapamycin (mTOR) Target Inhibitor as a Promising Strategy for Cancer Therapy

JAK1-IN-4 uinol A InChiKey: HGWLTZOMQZIUBW-UHFFFAOYSA-NJAK1 IN 4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12. 8 M and >30 M for JAK1, JAK2, and JAK3, respectively. JAK1 IN 4 inhibits STAT3 phosphorylation in NCI H 1975 cells (IC50, 227 nM). Product information CAS Number: 2091134 35 7 Molecular Weight: 521. 59 Formula: C26H32FN9O2 Chemical Name: (2R) 2 [(3R) 3,4 dimethylpiperazin 1 yl] N (3 {5 fluoro 2 [(3 methoxy 1 methyl 1H pyrazol 4 yl)amino]pyrimidin 4 yl} 1H indol 7

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