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SU6656 0022 Smiles: CNCC1C=CC(=CC=1)C1NC2=CC(F)=CC3C(=O)NCCC=1C=32

SKU: 71154529842

4.6
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Description

Smiles: CNCC1C=CC(=CC=1)C1NC2=CC(F)=CC3C(=O)NCCC=1C=32

Uncoupling between CD1d upregulation induced by retinoic acid and conduritol-B-epoxide and iNKT cell responsiveness

It competes with acetyl-CoA for the p300 Lys-CoA binding pocket selectively

25-65)34(59)11-12-62(35

SU6656 0022 Smiles: CNCC1C=CC(=CC=1)C1NC2=CC(F)=CC3C(=O)NCCC=1C=32SU6656 is a potent and selective dual inhibitor of Src family kinases and Aurora kinase. SU6656 modulates CTGF (connective tissue growth factor) expression in an ERK dependent manner. SU6656 induces caspase independent cell death in FRO anaplastic thyroid carcinoma cells and therapeutic synergy in human synovial sarcoma growth, invasion and angiogenesis in vivo. Product information CAS Number: 330161 87 0 Molecular Weight: 371. 45 Formula: C19H21N3O3S

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