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5-dihydro-5-(4(1H)-pyridinylidene)-1H-imidazol-2-yl]phenoxy]-N
2015 Jan 12
PD173074 treatment potently reduces viability of FGFR3-expressing KMS11 and KMS18 cells with IC50 of <20 nM
when compared with PP2
Docetaxel (Trihydrate) Size:Solid 2 mg 5-dihydro-5-(4(1H)-pyridinylidene)-1H-imidazol-2-yl]phenoxy]-NDocetaxel, also known as RP 56976, is a semi synthetic, second generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell cycle arrest at the G2 M phase and cell death. This agent also inhibits pro angiogenic factors such as vascular endothelial growth factor
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