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and in human KYSE180 oesophageal cancer cells with an IC50 of 1 µM
ICA-105665 (PF-04895162) has demonstrated broad spectrum antiseizure activity in multiple animal models including maximal electroshock
SB-224289 is a potent antagonist with pEC50 of 7
Altiratinib potently inhibits cellular proliferation in MET-amplified EBC-1 and MKN-45 cells
Benzamil hydrochloride G3-C2-NH2 TFA and in human KYSE180 oesophagealBenzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+ Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non selective Deg epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3 mediated Ca2+ activated currents, with an IC50 of 1. 1 M. Product information CAS Number: 161804 20 2 Molecular Weight: 356. 21 Formula:
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