Cilostazol-d11 bioside C EMT inhibitor-1 induces GSK3-β–mediated degradation

EMT inhibitor-1 induces GSK3-β–mediated degradation of the Hippo transducer TAZ

IC50=26 nM) in Jurkat

CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16

In relevant biological assays

Cilostazol-d11 bioside C EMT inhibitor-1 induces GSK3-β–mediated degradationProduct information CAS Number: 1073608 02 2 Molecular Weight: 380. 53 Formula: C20H27N5O2 Chemical Name: 6 (4 {1 [(1,2,2,3,3,4,4,5,5,6,6 H)cyclohexyl] 1H 1,2,3,4 tetrazol 5 yl}butoxy) 1,2,3,4 tetrahydroquinolin 2 one Smiles: [2H]C1(N2N=NN=C2CCCCOC2=CC3CCC(=O)NC=3C=C2)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H] InChiKey: RRGUKTPIGVIEKM SAGHCWGKSA N InChi: InChI=1S C20H27N5O2 c26 20 12 9 15 14 17(10 11 18(15)21 20)27 13 5 4 8 19 22