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9 L/kg) following intravenous administration (mouse 1
UU-T02 displays Ki values of 1
MK-4101 (40-80 mg/kg
Smiles: CC1(C)C[C@H]2[C@@]34C=C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](C)[C@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O)[C@@](C)(CO)[C@@H]6CC[C@@]5(C)[C@]3(C)C[C@@H](O)[C@@]2(CO4)CC1
BMS-P5 free base Catalog No.:M25989-C 9 L/kg) following intravenous administrationBMS P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS P5 free base blocks MM induced NET formation and delays progression of MM in a syngeneic mouse model. Product information CAS Number: 1550371 22 6 Molecular Weight: 472. 58 Formula: C27H32N6O2 Chemical Name: (3R,6S) 1 {2 [1 (cyclopropylmethyl) 1H pyrrolo[2,3 b]pyridin 2 yl] 7 methoxy 1 methyl 1H 1,3 benzodiazole 5 carbonyl} 6 methylpiperidin 3 amine