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It can also enhance learning and memory in aged rats
regulating deubiquitination activity of USP10 and USP13 by Beclin1 provides a mechanism for Beclin1 to control the levels of p53
is a novel first in class
It causes growth inhibition of normal and transformed cells but does not induce cell death
FG-4592 (Roxadustat) - HIF Prolyl-Hydroxylases Inhibitor. CAS# 808118-40-3 Catalog No.:M60263-10S It can also enhance learningFG 4592 (Roxadustat), CAS No. 808118 40 3, is a potent, selective and bioavailable inhibitor of hypoxia inducible factor prolyl hydroxylase. It is an analog of 2 oxoglutarate (2 OG) to inhibit HIF PH and prevent HIF turnover. While little has been published regarding the actions of this compound, similar HIF PH inhibitors suppress HIF degradation and in this way induce erythropoietin expression, promoting erythropoiesis or preventing anemia in vivo.
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