AZD-5597 Catalog No.:M22668-C Chks are protein kinases that

Chks are protein kinases that regulate either G1/S or G2/M transitions in the cell cycle

the less active isomer of (Z)-4-hydroxytamoxifen

and 10 μM) reduces cell viability in a concentration-dependent manner

11aS)-1-[(1S)-1-hydroxyethyl]-9a

AZD-5597 Catalog No.:M22668-C Chks are protein kinases thatAZD 5597 is a potent CDK inhibitor with IC50 values of 2 nM for CDK1 and CDK2, respectively . The cyclin dependent kinases (CDKs) are serine threonine protein kinases with roles in the regulation of the cell cycle, and also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells . AZD 5597 is a potent imidazole pyrimidine amide CDK inhibitor. In LoVo cells, AZD 5597 exhibited high level of anti proliferative