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CAS Number: 1883545-52-5
shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 µM) and JAK2 (50 µM)
Smiles: O=C1C(Cl)=C(C(=O)N1C1C=C(Cl)C(Cl)=CC=1)N1CCOCC1
connective tissue growth factor [CTGF] and fibroblast growth factor [FGF2])
Clozapine Catalog No.:M10647-2 CAS Number: 1883545-52-5Clozapine is an atypical antipsychotic drug because it binds to serotonin as well as dopamine receptors. Clozapine is a partial agonist at the 5 HT1A subunit of the serotonin receptor, putatively improving depression, anxiety, and the negative cognitive symptoms associated with schizophrenia. A direct interaction of clozapine with the GABAB receptor has also been shown. GABAB receptor deficient mice exhibit increased extracellular dopamine levels and
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