Netupitant metabolite N-desmethyl Netupitant ciclib) Negative and positive allosteric modulators

Negative and positive allosteric modulators of the P2X(7) receptor

whereas a phospholipase C-gamma1 (PLCgamma1)-defective line was resistant

4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21

which covalently modifies Cys481

Netupitant metabolite N-desmethyl Netupitant ciclib) Negative and positive allosteric modulatorsN desmethyl Netupitant is a metabolite of an antiemitic drug called Netupitant. Product information CAS Number: 290296 72 9 Molecular Weight: 564. 57 Formula: C29H30F6N4O Synonym: N desmethyl Netupitant Chemical Name: 2 [3,5 bis(trifluoromethyl)phenyl] N,2 dimethyl N [4 (2 methylphenyl) 6 (piperazin 1 yl)pyridin 3 yl]propanamide Smiles: CC(C)(C(=O)N(C)C1=CN=C(C=C1C1=CC=CC=C1C)N1CCNCC1)C1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F InChiKey: SRVSDBHUBFLSFE UHFFFAOYSA